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Peptide Strength Protocols Comparison Table: Benefits, Dosages & Results

Peptide Strength Protocols Comparison Table: Benefits, Dosages & Results

Dec 26, 2025

peptide strengh protocol
peptide strengh protocol

Just several peptide categories significantly enhance strength training outcomes through different mechanisms. Growth hormone peptides increase muscle mass and strength over time. IGF-1 LR3 provides rapid muscle growth and strength gains.

Healing peptides like BPC-157 and TB-500 allow you to train harder by accelerating recovery, and each serves specific purposes in a strength protocol.


This guide breaks down exactly which peptides benefit strength training, how each category works, specific protocols for strength versus mass versus recovery, realistic expectations for strength gains, proper dosing and cycling, and how to stack peptides for maximum performance enhancement.

Let's start with understanding how peptides enhance strength training.


How peptides enhance strength training performance

Peptides improve strength through multiple pathways beyond just building muscle. Learn complete peptide fundamentals in our what are peptides guide and how peptides work.

Direct muscle growth and strength

Mechanisms:

  • Increase protein synthesis in muscle cells

  • Enhance amino acid uptake

  • Stimulate satellite cell activation

  • Promote muscle fiber hypertrophy

  • Improve nutrient partitioning

Peptides in this category:

  • IGF-1 LR3 (most anabolic)

  • Growth hormone secretagogues (CJC-1295, Ipamorelin)

  • MGF (Mechano Growth Factor)

Result: Bigger, stronger muscles that generate more force.

See our what are peptides used for guide for comprehensive peptide applications.


Enhanced recovery and reduced injury

Mechanisms:

  • Accelerate tissue repair between training sessions

  • Reduce inflammation from training damage

  • Heal micro-tears faster

  • Support connective tissue (tendons, ligaments)

  • Allow higher training frequency

Peptides in this category:

  • BPC-157

  • TB-500

  • GHK-Cu

Result: Train harder, more often, with less injury risk. More volume = more strength gains.

Learn complete healing protocols in our best peptides for injury recovery guide, best peptides for joint pain, and best peptides for tendon repair.


Improved neural drive and force production

Mechanisms:

  • Enhance neuromuscular efficiency

  • Improve motor unit recruitment

  • Support nervous system recovery

  • Optimize muscle fiber activation

Peptides in this category:

  • Cerebrolysin (neurological support)

  • Semax (cognitive and neural enhancement)

Result: Better ability to recruit muscle fibers = more force production at same muscle size.


Optimized body composition

Mechanisms:

  • Reduce body fat while preserving muscle

  • Improve strength-to-weight ratio

  • Better leverage and force application

  • Enhanced muscle definition

Peptides in this category:

  • Growth hormone peptides (recomposition)

  • AOD 9604 (fat loss without muscle loss)

  • Semaglutide/Tirzepatide (weight management)

Result: Leaner body = better relative strength and power output.

See our best peptides for muscle growth guide for comprehensive muscle-building protocols.


Growth hormone peptides for strength training

These are the foundation of most strength enhancement protocols.

CJC-1295 (with or without DAC)

Primary benefits for strength:

  • Increased lean muscle mass over 3-6 months

  • Improved recovery between sessions

  • Better sleep quality (crucial for strength gains)

  • Enhanced fat loss while building muscle

  • Modest direct strength increases

Dosing for strength:

  • CJC-1295 (no DAC): 200-300mcg before bed, 5-7 days per week

  • CJC-1295 (with DAC): 1-2mg once or twice weekly

  • Typically stacked with GHRP for synergy

Timeline for strength gains:

  • Week 1-4: Improved recovery, better sleep

  • Week 8-12: Noticeable muscle mass increase

  • Month 4-6: Clear strength improvements (10-15% increase in major lifts)

Best for:

  • Long-term strength and mass building

  • Older athletes (35+) with declining GH

  • Body recomposition while gaining strength

Use our CJC-1295 dosage calculator for precise dosing.


Ipamorelin

Primary benefits for strength:

  • Growth hormone release without cortisol/prolactin increase

  • Clean muscle gains

  • Excellent recovery enhancement

  • Improved sleep architecture

  • Synergistic with CJC-1295

Dosing for strength:

  • 200-300mcg before bed, 5-7 days per week

  • Best results when combined with CJC-1295

  • Can dose 2-3x daily for maximum effect (pre-workout, post-workout, bedtime)

Timeline for strength gains:

  • Similar to CJC-1295

  • Works best in combination protocols

  • 3-6 months for significant strength increase

Best for:

  • Athletes who want GH benefits without side effects

  • Stacking with other peptides

  • Long-term strength development

See our Ipamorelin vs CJC-1295 comparison for detailed analysis.


GHRP-6 and GHRP-2

Primary benefits for strength:

  • Powerful growth hormone release

  • Significant muscle mass gains

  • Increased appetite (helps with bulking)

  • Strong recovery enhancement

Dosing for strength:

  • 100-300mcg, 2-3 times daily

  • Best on empty stomach

  • Powerful when stacked with CJC-1295

Timeline for strength gains:

  • Faster muscle gains than Ipamorelin

  • 8-16 weeks for significant strength improvements

  • More aggressive muscle building

Best for:

  • Bulking phases

  • Athletes who want aggressive muscle gain

  • Those who can manage increased appetite

Downsides:

  • Increases prolactin (monitor for side effects)

  • Very strong hunger (can be pro or con)


Hexarelin

Primary benefits for strength:

  • Most powerful GHRP for GH release

  • Rapid muscle growth

  • Significant strength gains

  • Enhanced recovery

Dosing for strength:

  • 100-200mcg, 2-3 times daily

  • Cycle for 4-8 weeks, then break (desensitization occurs)

  • Extremely potent

Timeline for strength gains:

  • Faster than other GHRPs

  • 4-8 weeks for noticeable strength increase

  • Requires cycling to maintain effectiveness

Best for:

  • Short-term strength boosts

  • Experienced peptide users

  • Aggressive bulking phases

Downsides:

  • Desensitization with continuous use

  • Increases cortisol and prolactin more than other GHRPs

  • Requires breaks


IGF-1 LR3: The most anabolic peptide for strength

IGF-1 LR3 is in a category by itself for muscle and strength building.

How IGF-1 LR3 builds strength

Mechanisms:

  • Directly stimulates muscle protein synthesis

  • Activates satellite cells (muscle stem cells)

  • Promotes hyperplasia (new muscle fiber creation)

  • Enhances nutrient uptake into muscles

  • Prevents muscle breakdown

Why it's so powerful:

  • Works locally in muscles (doesn't need GH conversion)

  • Longer half-life than natural IGF-1 (24+ hours vs 10 minutes)

  • More potent than growth hormone peptides


Dosing protocol for strength

Standard dosing:

  • 40-80mcg daily

  • Split into bilateral injections (both sides of target muscle) for local effect

  • Or single injection for systemic effect

Cycle length:

  • 4-6 weeks maximum

  • Followed by equal time off (4-6 weeks)

  • Not for continuous use

Timing:

  • Post-workout preferred (muscles are primed for growth)

  • OR pre-workout for nutrient partitioning during training


Expected strength gains

Realistic expectations:

  • 15-25% strength increase in major lifts over 4-6 weeks

  • 5-10 lbs muscle gain in single cycle

  • Noticeable size and strength within 2-3 weeks

Why results are dramatic:

  • Most anabolic peptide available

  • Directly builds muscle tissue

  • Works faster than growth hormone peptides


Important considerations

Risks and downsides:

  • Hypoglycemia risk (carry fast carbs during training)

  • Organ growth possible with chronic use

  • Requires cycling (not safe long-term)

  • Expensive

Best for:

  • Experienced users only

  • Specific strength/size goals

  • Short-term strength peaking

  • Advanced bodybuilders and powerlifters

Not for beginners: Start with GH peptides first.


Healing and recovery peptides for strength training

These don't build muscle directly but enable harder training.

BPC-157 for connective tissue and recovery

Benefits for strength training:

  • Prevents and heals tendon/ligament injuries

  • Reduces joint inflammation from heavy loading

  • Accelerates recovery between sessions

  • Allows higher training frequency and volume

  • Protects against overtraining injuries

Dosing for strength athletes:

  • 250-500mcg twice daily (500mcg-1mg total daily)

  • Injectable near problem areas or systemically

  • Can use continuously or cycle

Timeline:

  • Injury prevention: Ongoing use during heavy training

  • Acute injury: 4-8 weeks for healing

  • Recovery enhancement: Noticeable within 1-2 weeks

Best for:

  • Powerlifters and Olympic weightlifters (heavy joint stress)

  • Preventing chronic overuse injuries

  • Returning from injury

  • High-volume strength training

See our BPC-157 complete guide and BPC-157 dosage calculator.


TB-500 for deep tissue repair

Benefits for strength training:

  • Heals muscle strains faster

  • Repairs tendons and ligaments

  • Improves flexibility and range of motion

  • Reduces inflammation throughout body

  • Enhances recovery from intense training

Dosing for strength athletes:

  • Loading: 5-10mg per week (split into 2-3 injections) for 4-6 weeks

  • Maintenance: 2-5mg per week

  • Cycles of 8-16 weeks

Timeline:

  • Week 2-4: Improved recovery and reduced soreness

  • Week 4-8: Injuries healing faster

  • Week 8+: Significant tissue repair and enhanced training capacity

Best for:

  • Chronic injuries (shoulder, elbow, knee issues)

  • Improving mobility for better lifting mechanics

  • Aging athletes (35+)

  • High-intensity training recovery

See our TB-500 guide, TB-500 dosage calculator, and BPC-157 vs TB-500 comparison.


GHK-Cu (Copper Peptide) for tissue regeneration

Benefits for strength training:

  • Supports connective tissue health

  • Reduces exercise-induced inflammation

  • Enhances tissue repair

  • May improve vascularity

Dosing for strength athletes:

  • 1-2mg, 3-5 times per week

  • Injectable for systemic effects

  • Can combine with BPC-157 and TB-500

Best for:

  • Comprehensive recovery protocols

  • Aging athletes

  • Injury prevention

See our copper peptides guide.


Peptide strength protocol benefits comparison table

Here's how different peptides compare for strength training goals:

Peptide

Strength Gains

Muscle Mass

Recovery

Injury Prevention

Timeline

Difficulty

Best For

CJC-1295

Moderate

Good

Excellent

Moderate

3-6 months

Beginner

Long-term strength building

Ipamorelin

Moderate

Good

Excellent

Moderate

3-6 months

Beginner

Clean muscle gains

GHRP-6

Good

Excellent

Excellent

Moderate

2-4 months

Intermediate

Bulking phases

Hexarelin

Excellent

Excellent

Excellent

Moderate

4-8 weeks (cycles)

Advanced

Rapid strength gains

IGF-1 LR3

Excellent

Excellent

Good

Poor

4-6 weeks (cycles)

Advanced

Maximum muscle/strength

BPC-157

Poor (indirect)

Poor

Excellent

Excellent

2-4 weeks (recovery)

Beginner

Injury prevention

TB-500

Poor (indirect)

Moderate

Excellent

Excellent

4-8 weeks

Intermediate

Deep tissue repair

GHK-Cu

Poor (indirect)

Poor

Good

Good

4-8 weeks

Intermediate

Tissue regeneration

Key:

  • Strength gains: Direct impact on force production and lifting capacity

  • Muscle mass: Ability to build lean muscle tissue

  • Recovery: Speed of recovery between training sessions

  • Injury prevention: Protection against training-related injuries

  • Timeline: How long to see significant benefits

  • Difficulty: Beginner-friendly vs requires experience


peptides

Complete strength training peptide stacks

Combining peptides provides synergistic benefits.

Beginner stack: CJC-1295 + Ipamorelin

Protocol:

  • CJC-1295 (no DAC): 200mcg before bed

  • Ipamorelin: 200mcg before bed

  • Frequency: 5-7 days per week

  • Duration: 3-6 months minimum

Benefits:

  • Steady muscle growth

  • Improved recovery

  • Better sleep

  • Minimal side effects

  • Easy to manage

Expected results:

  • 5-10 lbs muscle gain over 6 months

  • 10-20% strength increase

  • Enhanced work capacity

Cost: Moderate ($100-200/month)


Intermediate stack: GH peptides + BPC-157

Protocol:

  • CJC-1295: 200mcg before bed

  • Ipamorelin: 200mcg before bed

  • BPC-157: 250-500mcg twice daily

  • Duration: 3-6 months

Benefits:

  • Muscle growth from GH peptides

  • Injury prevention from BPC-157

  • Can train harder and more frequently

  • Comprehensive support

Expected results:

  • 8-12 lbs muscle gain

  • 15-25% strength increase

  • Reduced injury incidence

  • Faster recovery

Cost: Moderate to high ($150-300/month)


Advanced stack: IGF-1 LR3 + GH peptides + healing peptides

Protocol:

  • IGF-1 LR3: 40-80mcg daily (4-6 week cycles)

  • CJC-1295: 200mcg before bed (continuous)

  • Ipamorelin: 200mcg before bed (continuous)

  • BPC-157: 500mcg twice daily (continuous)

  • TB-500: 5-10mg per week loading, then 2-5mg maintenance

Benefits:

  • Maximum anabolic environment

  • Rapid muscle and strength gains

  • Excellent recovery

  • Injury protection

Expected results:

  • 10-15 lbs muscle gain in 4-6 weeks (IGF-1 cycle)

  • 20-35% strength increase

  • Dramatic body composition improvement

Cost: High ($300-500+/month)

Experience required: Advanced users only. Requires proper cycling, monitoring, and understanding of all peptides.

Learn complete stacking strategies in our peptide stacks guide, can you cycle different peptides guide, and common peptide mistakes beginners make.


Dosing and cycling for strength protocols

Proper protocols maximize gains and minimize risks.

General principles

Start low:

  • Begin with minimum effective dose

  • Assess tolerance for 2-4 weeks

  • Increase if needed and tolerated

Cycle appropriately:

  • Growth hormone peptides: Can use 3-6+ months continuously

  • IGF-1 LR3: Must cycle 4-6 weeks on, 4-6 weeks off

  • Healing peptides: Can use continuously or cycle based on need

Monitor progress:

  • Track strength (weights, reps)

  • Monitor body composition

  • Watch for side effects

  • Adjust dosing based on results


Timing relative to training

Pre-workout:

  • IGF-1 LR3 (nutrient partitioning)

  • Optional: GHRP-6 (some users prefer)

Post-workout:

  • IGF-1 LR3 (muscle building)

  • BPC-157 (recovery)

Before bed:

  • CJC-1295 + Ipamorelin (GH release during sleep)

  • Growth happens during sleep

Throughout day:

  • BPC-157 (twice daily)

  • TB-500 (based on weekly total)

Learn proper injection technique in our how to inject peptides guide and mixing protocols in our how to reconstitute peptides guide. Use our free peptide reconstitution calculator for exact measurements.


Sample 16-week strength protocol

Weeks 1-16 (base):

  • CJC-1295: 200mcg nightly

  • Ipamorelin: 200mcg nightly

  • BPC-157: 250mcg twice daily

Weeks 1-6 (IGF-1 cycle):

  • Add IGF-1 LR3: 60mcg post-workout

Weeks 7-12 (off IGF-1):

  • Continue base protocol only

Weeks 13-16 (optional second IGF-1 cycle):

  • Add IGF-1 LR3: 60mcg post-workout

Expected outcome:

  • 15-20 lbs muscle gain

  • 25-40% strength increase in major lifts

  • Minimal injuries

  • Excellent body composition

Use our peptide cycle planning guide for detailed cycle planning, peptide dosage chart for reference doses, and how to calculate peptide dosages for precision.


Realistic strength gain expectations

Understanding what's actually achievable prevents disappointment and unrealistic goals.

Strength gains by peptide protocol

Beginner protocol (CJC/Ipa only):

  • 3 months: 10-15% strength increase

  • 6 months: 15-25% strength increase

  • Muscle gain: 5-10 lbs

Intermediate protocol (GH + BPC-157):

  • 3 months: 15-20% strength increase

  • 6 months: 20-30% strength increase

  • Muscle gain: 8-15 lbs

Advanced protocol (IGF-1 + full stack):

  • 6 weeks (single IGF-1 cycle): 15-20% strength increase

  • 4-6 months (multiple cycles): 30-50% strength increase

  • Muscle gain: 15-25 lbs

Factors affecting results:

  • Training quality (progressive overload essential)

  • Nutrition (caloric surplus for strength gains)

  • Sleep (7-9 hours nightly)

  • Training experience (beginners gain faster)

  • Genetics

  • Age (older athletes may see bigger relative improvements)


Comparison to natural training

Natural strength gains (optimal training and nutrition):

  • Beginner: 20-30% strength increase in first year

  • Intermediate: 10-15% per year

  • Advanced: 5-10% per year

With peptides:

  • Accelerated timeline (compress 12 months into 6)

  • Higher ceiling (surpass natural potential)

  • Better recovery allows more volume

Peptides don't replace training:

  • Still need progressive overload

  • Proper programming essential

  • Nutrition must support gains

  • Peptides enhance but don't replace fundamentals


Safety and side effects for strength protocols

Peptides are generally safe but require awareness.

Common side effects by peptide type

Growth hormone peptides:

  • Water retention (temporary)

  • Lethargy initially (adapts within weeks)

  • Carpal tunnel symptoms (rare, high doses)

  • Insulin resistance (monitor with long-term use)

IGF-1 LR3:

  • Hypoglycemia (keep fast carbs on hand)

  • Jaw/facial bone growth (with chronic use)

  • Organ enlargement (long-term misuse)

Healing peptides:

  • Minimal side effects

  • Occasionally: fatigue, headache (rare)


Monitoring and bloodwork

Baseline testing before starting:

  • IGF-1 levels

  • Thyroid panel (T3, T4, TSH)

  • Fasting glucose and insulin

  • Lipid panel

  • Liver and kidney function

Follow-up testing:

  • Every 3-6 months during protocol

  • Monitor IGF-1 (ensure not excessively elevated)

  • Check glucose metabolism

  • Liver/kidney function


Contraindications

Avoid peptides if:

  • Active cancer (GH/IGF-1 can promote tumor growth)

  • Diabetic without physician oversight

  • Significant organ disease

Use caution if:

  • Family history of cancer

  • Pre-diabetic

  • Taking medications that affect blood sugar

See our peptide safety and risks guide for comprehensive safety information.


Nutrition and training optimization with peptides

Peptides enhance results but require proper foundation.

Nutrition for strength with peptides

Caloric surplus required:

  • Minimum +300-500 calories above maintenance

  • Higher protein (1.2-1.5g per lb bodyweight)

  • Adequate carbs (support training and IGF-1 effectiveness)

  • Healthy fats (hormone production)

Timing:

  • Pre-workout: Carbs and protein

  • Post-workout: High protein, moderate carbs (especially with IGF-1)

  • Throughout day: Regular protein feedings

Hydration:

  • Increased water needs (GH peptides cause retention)

  • Minimum 1 gallon daily

  • More during training


Training programming

Progressive overload essential:

  • Increase weight, reps, or volume over time

  • Peptides support this but don't replace it

  • Track all training metrics

Frequency:

  • Peptides support higher frequency (better recovery)

  • Can train each muscle 2-3x weekly instead of 1x

  • Listen to body despite enhanced recovery

Volume:

  • Can tolerate higher volume with peptides

  • Start conservatively, add volume gradually

  • Recovery peptides allow aggressive training


Sleep and recovery

Sleep critical:

  • 7-9 hours nightly minimum

  • GH release primarily during deep sleep

  • Peptides enhance sleep quality

Active recovery:

  • Light cardio

  • Mobility work

  • Massage, sauna

Rest days:

  • Still necessary despite enhanced recovery

  • 1-2 full rest days weekly


How you can use SeekPeptides for strength protocols

SeekPeptides provides personalized strength and performance protocols tailored to your training goals. Get customized peptide stacks showing exactly which peptides to use for your strength phase, proper dosing schedules, and cycle planning that aligns with your training blocks.

Our AI advisor helps you troubleshoot protocols, adjust doses based on results, and determine when to add or remove specific peptides.

Access complete research on peptide mechanisms for muscle growth and strength, clinical evidence from our peptide research library, and proven protocols from experienced users.

Track your strength progression and body composition changes throughout peptide cycles using our peptide dosing tools and cycle planning resources to optimize your protocols.

Learn how to properly store and handle your peptides with our peptide storage guide and reconstitution guide for best results.


Final thoughts

Peptides offer significant benefits for strength training through multiple pathways.

Growth hormone peptides provide steady muscle and strength gains over months. IGF-1 LR3 delivers rapid, dramatic muscle growth and strength increases in short cycles. Healing peptides prevent injuries and enhance recovery, allowing harder, more frequent training.

The best approach combines growth and healing peptides. CJC-1295 + Ipamorelin provides the foundation for beginners. Advanced users add IGF-1 LR3 for explosive gains. BPC-157 and TB-500 protect against injuries and speed recovery throughout.

Realistic expectations matter. Expect 10-25% strength gains in 3-6 months with beginner protocols, 30-50% with advanced protocols. Results require proper training, nutrition, and recovery - peptides enhance but don't replace fundamentals.

Start conservatively, track progress, adjust based on results. Peptides are powerful tools for strength training when used intelligently.

Your strength gains accelerate with the right peptide protocol. Choose based on your experience level, goals, and commitment.


Frequently Asked Questions About Peptide Strength Protocols

What peptides are best for strength training?

The most effective peptides for strength include BPC-157 for recovery, TB-500 for muscle repair, Ipamorelin for growth hormone release, and CJC-1295 for sustained muscle growth. Many athletes use peptide stacks combining multiple compounds for synergistic effects.


How long does it take to see strength gains from peptides?

Most users report noticeable strength improvements within 4-6 weeks. Peptides for muscle growth like Ipamorelin show faster results (2-3 weeks) while recovery peptides like TB-500 take 4-8 weeks for full benefits.


What's the proper dosage for strength-focused peptide protocols?

Dosages vary by peptide: BPC-157 (250-500mcg daily), TB-500 (2-5mg twice weekly), Ipamorelin (200-300mcg 2-3x daily), CJC-1295 (1-2mg weekly). Always start at lower doses and adjust based on response. Use our peptide dosage calculator for precise measurements.


Can I stack multiple peptides for better strength results?

Yes, peptide stacking is common for strength training. Popular combinations include BPC-157 + TB-500 for recovery, or Ipamorelin + CJC-1295 for growth. See our peptide stacking guide and peptide stack calculator to plan your protocol safely.


Are peptides safer than steroids for building strength?

Generally yes - peptides have fewer side effects than anabolic steroids and work with your body's natural processes. They don't suppress testosterone production or cause organ damage like traditional steroids.


How do I properly reconstitute and store strength peptides?

Use bacteriostatic water for reconstitution - our peptide reconstitution calculator ensures accurate mixing. Store reconstituted peptides in the refrigerator (2-8°C). Reconstituted peptides typically last 2-4 weeks when properly stored.


What are common mistakes to avoid with peptide strength protocols?

Common errors include improper dosing, inconsistent timing, inadequate nutrition, and skipping post-cycle therapy. Many beginners also mix peptides incorrectly or use contaminated water.


Do I need to cycle peptides for strength training?

Yes, most strength protocols benefit from cycling - typically 8-12 weeks on followed by 4-6 weeks off. This prevents receptor desensitization and maintains effectiveness.



Helpful resources for strength peptides


Related guides worth reading


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peptdies

"I had struggled with acne for years and nothing worked. Was skeptical about peptides but decided to try the skin healing protocol SeekPeptides built for me. Within 6 weeks I noticed a huge difference, and by week 10 my skin was completely transformed. OMG, I still can't believe how clear it is now. Changed my life. Thanks."

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peptides

“Used to buy peptides and hope for the best. Now I have a roadmap and I'm finally seeing results, lost 53 lbs so far.”

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"I'm 52 and was starting to look exhausted all the time, dark circles, fine lines, just tired. Started my longevity protocol 3 months ago and people keep asking if I got work done. I just feel like myself again."

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