IPAMORELIN VS CJC-1295
IPAMORELIN VS CJC-1295
Complete comparison of the two most popular GH-releasing peptides. Mechanisms, results, timing, and which one works best for muscle growth, fat loss, and anti-aging.
Complete comparison of the two most popular GH-releasing peptides. Mechanisms, results, timing, and which one works best for muscle growth, fat loss, and anti-aging.
ESSENTIALS
The key differences between Ipamorelin and CJC-1295
The key differences between Ipamorelin and CJC-1295
Features
Ipamorelin
CJC-1295
Best For
Multiple daily pulses, flexibility
Long-lasting steady GH elevation
Duration of action
2-3 hours
6-8 days
Dosing frequency
2-3x daily
2x weekly
GH pulse pattern
Sharp spikes (natural)
Steady elevation (constant)
Side effects
Very rare
Very rare
Monthly cost
$80-150
$100-180
Features
Ipamorelin
CJC-1295
Best For
Multiple daily pulses, flexibility
Long-lasting steady GH elevation
Duration of action
2-3 hours
6-8 days
Dosing frequency
2-3x daily
2x weekly
GH pulse pattern
Sharp spikes (natural)
Steady elevation (constant)
Side effects
Very rare
Very rare
Monthly cost
$80-150
$100-180
THE BASICS
What each peptide is and how it works
What each peptide is and how it works
Ipamorelin
Ipamorelin is a growth hormone secretagogue (GHS) that stimulates your pituitary gland to release natural growth hormone in pulses. It's a pentapeptide (5 amino acids) that mimics ghrelin, creating natural GH spikes similar to youth. Works quickly (30 minutes) and clears fast (2-3 hours).
Activating ghrelin receptors in pituitary
Activating ghrelin receptors
Triggering natural GH pulse release
Promoting new blood vessel formation
Mimicking body's natural rhythm
Slowing gastric emptying
Creating 2-3 hour GH elevation per dose
Creating 2-3 hour GH elevation
Allowing multiple pulses throughout day
Allowing multiple pulses throughout day
Not affecting cortisol or prolactin
Not affecting cortisol or prolactin
CJC-1295
CJC-1295 (with DAC) is a growth hormone-releasing hormone (GHRH) analog that extends the body's GH pulses. The Drug Affinity Complex (DAC) extends its half-life to 6-8 days, creating steady elevated GH levels. One injection maintains elevated GH for a week.
Mimicking growth hormone-releasing hormone
Mimicking growth hormone-releasing
Extending natural GH pulses
Promoting new blood vessel formation
Maintaining elevated baseline GH
Maintaining elevated baseline GH
Creating 6-8 day duration per injection
Creating 6-8 day duration per injection
Amplifying body's existing pulses
Amplifying body's existing pulses
Working synergistically with natural rhythms
Working synergistically
COMPARISON
Complete feature comparison
Complete feature comparison
Every aspect compared side-by-side, timing, effectiveness, convenience, and more
Every aspect compared side-by-side, timing, effectiveness, convenience, and more
Category
Ipamorelin
CJC-1295
Half-life
2-3 hours
6-8 days
Injection frequency
2-3x daily
2x weekly
GH release pattern
Pulsatile (spikes)
Steady elevation
Time to peak
30-45 minutes
Gradual over days
Best timing
Morning, post-workout, bedtime
Anytime (long-lasting)
Flexibility
High (can time around meals)
Low (always active)
Hunger increase
Mild (ghrelin mimetic)
Minimal
Sleep quality
Excellent
Very good
Muscle growth
Good
Good
Fat loss
Good
Very good
Recovery
Excellent
Very good
Anti-aging
Excellent
Excellent
Cortisol impact
None
None
Category
Ipamorelin
CJC-1295
Half-life
2-3 hours
6-8 days
Injection frequency
2-3x daily
2x weekly
GH release pattern
Pulsatile (spikes)
Steady elevation
Time to peak
30-45 minutes
Gradual over days
Best timing
Morning, post-workout, bedtime
Anytime (long-lasting)
Flexibility
High (can time around meals)
Low (always active)
Hunger increase
Mild (ghrelin mimetic)
Minimal
Sleep quality
Excellent
Very good
Muscle growth
Good
Good
Fat loss
Good
Very good
Recovery
Excellent
Very good
Anti-aging
Excellent
Excellent
Cortisol impact
None
None
Category
Ipamorelin
CJC-1295
Half-life
2-3 hours
6-8 days
Injection frequency
2-3x daily
2x weekly
GH release pattern
Pulsatile (spikes)
Steady elevation
Time to peak
30-45 minutes
Gradual over days
Best timing
Morning, post-workout, bedtime
Anytime (long-lasting)
Flexibility
High (can time around meals)
Low (always active)
Hunger increase
Mild (ghrelin mimetic)
Minimal
Sleep quality
Excellent
Very good
Muscle growth
Good
Good
Fat loss
Good
Very good
Recovery
Excellent
Very good
Anti-aging
Excellent
Excellent
Cortisol impact
None
None
CHOOSE
Which peptide for your situation
Which peptide for your situation
Choose based on your lifestyle, goals, and commitment level
Choose based on your lifestyle, goals, and commitment level
Choose Ipamorelin if you:
Choose Ipamorelin if you:
Want control over timing
Want control over timing
Prefer natural pulsatile rhythm
Prefer natural pulsatile rhythm
Need flexibility with schedule
Need flexibility with schedule
Want to time around meals/training
Want to time around meals/training
Like mimicking youth patterns
Like mimicking youth patterns
Want 2-3 pulses per day
Want 2-3 pulses per day
Are sensitive to constant elevation
Are sensitive to constant elevation
Need to stop/start easily
Need to stop/start easily
Choose CJC-1295 if you:
Choose CJC-1295 if you:
Want convenience (2x weekly)
Want convenience (2x weekly)
Prefer steady stable levels
Prefer steady stable levels
Don't want daily injections
Travel frequently
Travel frequently
Want "set and forget" approach
Want "set and forget" approach
Prioritize fat loss
Prioritize fat loss
Need consistent 24/7 elevation
Need consistent 24/7 elevation
Have busy schedule
Have busy schedule
Stack both (most common) if you:
Use both if you:
Want maximum GH optimization
Serious about body composition
Serious about body composition
CJC provides baseline
CJC provides baseline
Ipamorelin provides spikes
Have insurance covering semaglutide
Best of both worlds
Best of both worlds
Budget allows ($200-300/month)
Want synergistic effects
Want synergistic effects
FREE TOOLS
Explore all peptide calculators
Explore all peptide calculators
Tools to optimize every aspect of your peptide protocol
Tools to optimize every aspect of your peptide protocol
Dosage Calculator
Calculate precise dosages, injection volumes, and frequency for all major peptides based on your body weight.
Reconstitution Calculator
Concentration ratios, injection volumes, and IU measurements when mixing peptide powder with bacteriostatic water.
BPC-157 Calculator
Get injury-specific BPC-157 dosing protocols with cycle length recommendations for optimal healing results.
TB-500 Calculator
Calculate loading and maintenance phase protocols for TB-500 based on injury severity and recovery goals.
Dosage Calculator
Calculate precise dosages, injection volumes, and frequency for all major peptides based on your body weight.
Reconstitution Calculator
Concentration ratios, injection volumes, and IU measurements when mixing peptide powder with bacteriostatic water.
BPC-157 Calculator
Get injury-specific BPC-157 dosing protocols with cycle length recommendations for optimal healing results.
TB-500 Calculator
Calculate loading and maintenance phase protocols for TB-500 based on injury severity and recovery goals.
Dosage Calculator
Calculate precise dosages, injection volumes, and frequency for all major peptides based on your body weight.
Reconstitution Calculator
Concentration ratios, injection volumes, and IU measurements when mixing peptide powder with bacteriostatic water.
BPC-157 Calculator
Get injury-specific BPC-157 dosing protocols with cycle length recommendations for optimal healing results.
TB-500 Calculator
Calculate loading and maintenance phase protocols for TB-500 based on injury severity and recovery goals.
FAQ
Frequently asked questions
Frequently asked questions
Everything you need to know about Ipamorelin, CJC-1295, and using them together
Everything you need to know about Ipamorelin, CJC-1295, and using them together
Which one is better for muscle growth?
Ipamorelin provides timed pulses around workouts for better acute recovery. CJC-1295 provides steady anabolic environment. For pure muscle growth, Ipamorelin edges ahead. For overall body composition (muscle + fat loss), CJC-1295 slightly better. Stacking both gives best results.
Which one is better for muscle growth?
Ipamorelin provides timed pulses around workouts for better acute recovery. CJC-1295 provides steady anabolic environment. For pure muscle growth, Ipamorelin edges ahead. For overall body composition (muscle + fat loss), CJC-1295 slightly better. Stacking both gives best results.
Which one is better for muscle growth?
Ipamorelin provides timed pulses around workouts for better acute recovery. CJC-1295 provides steady anabolic environment. For pure muscle growth, Ipamorelin edges ahead. For overall body composition (muscle + fat loss), CJC-1295 slightly better. Stacking both gives best results.
Can I use both together?
Can I use both together?
Can I use both together?
Which is easier to use?
Which is easier to use?
Which is easier to use?
Why does Ipamorelin need multiple daily doses?
Why does Ipamorelin need multiple daily doses?
Why does Ipamorelin need multiple daily doses?
What's the difference between CJC-1295 with DAC and without DAC?
What's the difference between CJC-1295 with DAC and without DAC?
What's the difference between CJC-1295 with DAC and without DAC?
Do these suppress natural GH production?
Do these suppress natural GH production?
Do these suppress natural GH production?
Will I lose gains when I stop?
Will I lose gains when I stop?
Will I lose gains when I stop?
Ready to optimize your peptide use?
Ready to optimize your peptide use?
Know you're doing it safely, save hundreds on wrong peptides, and finally see the results you've been working for
Know you're doing it safely, save hundreds on wrong peptides, and finally see the results you've been working for